RESOURCE USE, COSTS, AND APPROVAL TIMES FOR PLANNING AND PREPARING A RANDOMIZED CLINICAL TRIAL BEFORE AND AFTER THE IMPLEMENTATION OF THE NEW SWISS HUMAN RESEARCH LEGISLATION.

BackgroundThe preparation of a randomized controlled trial (RCT) requires substantial resources and the administrative processes can be burdensome.To facilitate the conduct of RCTs it is important to better understand cost drivers.In January 2014 the enactment of the new Swiss Legislation on Human Research (LHR) considerably changed the regulatory

Solanum sisymbriifolium Lam.(Solanaceae), an undershrub species, was first identified at an upland site in the suburb of Gorakhpur town during a broad survey on the distribution and abundance of grassland and old-field species of northeastern Sexy Lingerie Uttar Pradesh.The species was first noticed in August 2012, and by the start of 2014 it showe

This systematic review aimed to update the management of sleep bruxism (SB) in adults, as diagnosed using polysomnography (PSG) and/or electromyography (EMG).Management methods covered were oral appliance therapy (OAT) with stabilization splints, cognitive-behavioral therapy (CBT), biofeedback therapy (BFT), and Draw Reins pharmacological therapy.A

This study focused on implementation of the Sustainable Development Goal (SDG) 11 indicators, at local scale, useful in monitoring urban social resilience.For this purpose, the study focused on updating the distribution map of the migrant population regularly residing in Bari and a neighboring town in Southern Italy.The area is exposed to increasin